Zaymiey

🔬 Biology  ·  Biotechnology: Principles and Processes  ·  NEET

The Cas9 protein in CRISPR is guided to its target by:

Answer: Guide RNA (gRNA) complementary to the target DNA sequence.

  • A Protein-protein interactions with transcription factor complexes
  • B Guide RNA (gRNA) complementary to the target DNA sequence
  • C Restriction enzymes that recognize specific palindromic sequences
  • D Diffusible chemical signals released by the target cell

Correct answer: B. Guide RNA (gRNA) complementary to the target DNA sequence

Explanation: CRISPR-Cas9: a guide RNA (gRNA) is designed to match the target DNA sequence. It directs the Cas9 nuclease to cut at that specific location.

PlasmidGene of interestcutrestriction enzymeligateRecombinantplasmidHost cell

Recombinant DNA technology: a gene of interest and plasmid are cut by the same restriction enzyme, ligated into a recombinant plasmid, and introduced into a host cell.

Concept context

Recombinant DNA, GMOs, PCR, CRISPR, and biotechnology applications. Growing importance in NEET.

Read the full Biotechnology: Principles and Processes notes →