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🔬 Biology  ·  Biotechnology: Principles and Processes  ·  NEET

In the PCR cycle, the step of annealing requires the temperature to be lowered after denaturation. What happens during annealing?

Answer: Primers bind to the complementary single strands.

  • A The two DNA strands separate
  • B The DNA is permanently denatured
  • C Taq polymerase synthesises entirely new DNA strands
  • D Primers bind to the complementary single strands

Correct answer: D. Primers bind to the complementary single strands

Explanation: After denaturation separates the strands, the temperature is lowered so that the two sets of primers anneal (hybridise) to the complementary regions of the single strands.

PlasmidGene of interestcutrestriction enzymeligateRecombinantplasmidHost cell

Recombinant DNA technology: a gene of interest and plasmid are cut by the same restriction enzyme, ligated into a recombinant plasmid, and introduced into a host cell.

Concept context

Recombinant DNA, GMOs, PCR, CRISPR, and biotechnology applications. Growing importance in NEET.

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