Zaymiey

🧪 Chemistry  ·  Haloalkanes & Haloarenes  ·  NEET & JEE

In nucleophilic aromatic substitution (SNAr) on 2,4-dinitrochlorobenzene, the mechanism involves:

Answer: Formation of a Meisenheimer complex (carbanion intermediate) followed by departure of Cl-.

  • A A simple SN2 backside attack directly on the sp<sup>2</sup> ring carbon bearing chlorine as generally observed
  • B Formation of a Meisenheimer complex (carbanion intermediate) followed by departure of Cl-
  • C A free radical chain mechanism initiated by homolytic C-Cl cleavage in typical laboratory settings
  • D A carbocation (arenium ion) intermediate, as seen in electrophilic substitution under usual circumstances

Correct answer: B. Formation of a Meisenheimer complex (carbanion intermediate) followed by departure of Cl-

Explanation: SNAr proceeds via an addition-elimination mechanism: the nucleophile attacks the carbon bearing the leaving group to form a stable Meisenheimer complex (stabilised by the electron-withdrawing NO₂ groups); then Cl⁻ leaves.

SN2: one stepNu-CX-backside attackNuC+ X-Inversion of configuration(Walden inversion)SN1: two stepsCX-slow: leaving group exits+CcarbocationNu-Planar intermediate givesracemisation (both faces attacked)

SN2 proceeds in a single step with backside attack and inversion of configuration, while SN1 forms a planar carbocation intermediate first, leading to racemisation.

Concept context

Study carbon-halogen compounds: how they are made, how they react via SN1/SN2 and elimination, their stereochemistry, and their environmental impact.

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