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🧪 Chemistry  ·  Coordination Compounds  ·  NEET & JEE

Which complex is used as an anticancer drug?

Answer: Cisplatin [cis-Pt(NH 3 ) 2 Cl 2 ].

  • A Cisplatin [cis-Pt(NH<sub>3</sub>)<sub>2</sub>Cl<sub>2</sub>]
  • B [Co(NH<sub>3</sub>)<sub>6</sub>]Cl3 in routine practice
  • C [Fe(CN)<sub>6</sub>]4- overall in most cases
  • D [Cu(NH<sub>3</sub>)4]2+ under typical conditions

Correct answer: A. Cisplatin [cis-Pt(NH<sub>3</sub>)<sub>2</sub>Cl<sub>2</sub>]

Explanation: Cisplatin (cis-diamminedichloroplatinum(II)) crosslinks DNA strands in cancer cells, inhibiting replication.

Octahedralcoordination no. 6e.g. [Co(NH3)6]3+Tetrahedralcoordination no. 4e.g. [Ni(CO)4]Square Planarcoordination no. 4e.g. [Pt(NH3)2Cl2]

The three common coordination geometries: octahedral (6 ligands), tetrahedral (4 ligands), and square planar (4 ligands in one plane).

Concept context

Study of compounds where a central metal atom is bonded to surrounding ligands. Covers nomenclature, types of isomerism, bonding theories (VBT, CFT), and applications in medicine, photography, and industry.

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