Answer: Loss of 3D structure while primary structure remains intact.
- A Loss of 3D structure while primary structure remains intact
- B Hydrolysis of the peptide bonds linking adjacent amino acids
- C Formation of new covalent bonds within the polypeptide chain
- D Reduction of the protein's peptide carbonyl groups
Correct answer: A. Loss of 3D structure while primary structure remains intact
Explanation: Denaturation disrupts secondary, tertiary, and quaternary structures without breaking peptide bonds.
Two amino acids join via a condensation reaction: the carboxyl -OH of one and an amine -H of the other are eliminated as water, leaving a peptide bond (-CO-NH-) linking them into a dipeptide; repeating this builds a full protein chain.
Concept context
The chemistry of life: carbohydrates, proteins, lipids, nucleic acids, enzymes, and vitamins. Understand their structures, classification, and biological functions. Highly relevant for NEET and Class 12 board exams.