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🧪 Chemistry  ·  Amines  ·  NEET & JEE

Which reaction produces an amine from an amide using Br<sub>2</sub> and NaOH?

Answer: Hofmann degradation.

  • A Hofmann degradation
  • B Curtius rearrangement
  • C Gabriel synthesis
  • D Schmidt reaction

Correct answer: A. Hofmann degradation

Explanation: Hofmann degradation or bromamide reaction converts RCONH<sub>2</sub> to RNH<sub>2</sub> (one less carbon).

Why Aniline Is a Weaker Base Than MethylamineNCH₃lone pair fully availableMethylamineN donates electrons freely → STRONG baseNlone pair delocalised into ringAniline

In aniline, the nitrogen's lone pair is pulled into the benzene ring through resonance, leaving less electron density available to accept a proton - which is why aniline is a much weaker base than methylamine, where the lone pair is fully available.

Concept context

Nitrogen-containing organic compounds. Covers classification (primary, secondary, tertiary), basicity comparison, preparation methods, and reactions including diazotization and coupling, key for understanding dyes and pharmaceuticals.

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