Answer: Streptokinase forms a complex with plasminogen, inducing a conformational change that activates it to plasmin, which then lyses fibrin clots.
- A Streptokinase cleaves fibrin strands directly and immediately, rarely involving plasminogen in the process in typical laboratory settings
- B Streptokinase forms a complex with plasminogen, inducing a conformational change that activates it to plasmin, which then lyses fibrin clots
- C Streptokinase is clinically effective mainly on blood clots that are less than roughly one hour old under usual circumstances according to most researchers
- D Streptokinase inhibits thrombin activity directly mainly to prevent the formation of new blood clots in the majority of cases studied as widely reported
Correct answer: B. Streptokinase forms a complex with plasminogen, inducing a conformational change that activates it to plasmin, which then lyses fibrin clots
Explanation: Unlike direct thrombolytics, streptokinase is an indirect thrombolytic - it forms a 1:1 complex with plasminogen, causing a conformational change that exposes the active site to generate plasmin, which then degrades fibrin in clots.
Sewage passes through physical removal (primary), then aerobic biological treatment where microbes form flocs that consume organic matter (secondary); the settled activated sludge is then digested anaerobically to produce biogas - a deliberate switch from aerobic to anaerobic conditions between stages.
Concept context
Microorganisms in food, medicine, sewage treatment, biocontrol, and biofertilizers