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🔬 Biology  ·  Immune System  ·  NEET

What is the main antibody class in blood serum?

Answer: IgG.

  • A IgA
  • B IgM
  • C IgE
  • D IgG

Correct answer: D. IgG

Explanation: IgG is the most abundant antibody in blood serum (~80%). It provides long-term immunity, can cross the placenta to protect the fetus, and is the main antibody of secondary immune responses.

Antibody (Y-shaped) Binding an Antigenconstant region (Fc)variable regionvariable regionantigenantigen2 identical heavy chains+ 2 identical light chains

An antibody is Y-shaped, with two identical antigen-binding sites at the tips of the variable regions - each shaped to recognise one specific antigen - while the constant (Fc) region at the base is recognised by immune cells to trigger further responses.

Concept context

Innate and adaptive immunity, B cells, T cells, antibodies, vaccines, and immune disorders. Critical for NEET.

Read the full Immune System notes →