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🔬 Biology  ·  Immune System  ·  NEET

The rejection of a transplanted organ by the body is brought about mainly by:

Answer: Cell-mediated immunity.

  • A The innate skin barrier
  • B Antibodies present in tears
  • C Cell-mediated immunity
  • D Passively acquired immunity

Correct answer: C. Cell-mediated immunity

Explanation: Graft rejection is chiefly a cell-mediated response - T cells recognise the foreign MHC on the transplanted tissue.

Antibody (Y-shaped) Binding an Antigenconstant region (Fc)variable regionvariable regionantigenantigen2 identical heavy chains+ 2 identical light chains

An antibody is Y-shaped, with two identical antigen-binding sites at the tips of the variable regions - each shaped to recognise one specific antigen - while the constant (Fc) region at the base is recognised by immune cells to trigger further responses.

Concept context

Innate and adaptive immunity, B cells, T cells, antibodies, vaccines, and immune disorders. Critical for NEET.

Read the full Immune System notes →