Answer: Altering the zona pellucida so no more sperm can bind.
- A Increasing the total number of sperm acrosomes
- B Altering the zona pellucida so no more sperm can bind
- C Dissolving the corona radiata
- D Halting meiosis of the oocyte
Correct answer: B. Altering the zona pellucida so no more sperm can bind
Explanation: Release of cortical granules modifies the zona pellucida (the zona reaction), blocking the entry of additional sperm and thus preventing polyspermy.

The human male reproductive system: sperm formed in the testis mature in the epididymis and travel via the vas deferens, mixing with secretions of the seminal vesicle, prostate and bulbourethral glands. Image: Wumingbai, CC BY-SA 4.0, via Wikimedia Commons.
Concept context
Male and female reproductive systems, gametogenesis, fertilization, implantation, pregnancy, and reproductive health.