Answer: Released into the blood from the posterior pituitary, which mainly stores and releases them rather than producing them.
- A Released into the blood from the posterior pituitary, which mainly stores and releases them rather than producing them
- B Converted into TSH and ACTH respectively before reaching their target organs as generally observed in typical laboratory settings
- C Synthesized in the posterior pituitary itself and transported to the hypothalamus for storage in most reference accounts
- D Released directly from hypothalamic neurons into cerebrospinal fluid without entering the bloodstream under normal conditions
Correct answer: A. Released into the blood from the posterior pituitary, which mainly stores and releases them rather than producing them
Explanation: Oxytocin and ADH are synthesized by hypothalamic neurons, transported along axons, and released into the blood from the posterior pituitary (neurohypophysis), which acts as a storage and release site.
The hypothalamus releases hormones that direct the pituitary, which releases its own trophic hormone to a target gland; that gland's hormone output then feeds back (dashed lines) to suppress both the pituitary and hypothalamus once levels are sufficient - a self-correcting loop running the entire endocrine system.
Concept context
The endocrine glands, hormone classification and mechanism of action, and negative feedback regulation.