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🔬 Biology  ·  Chemical Coordination and Integration  ·  NEET

Atrial natriuretic factor (ANF) is released by the heart's atrial wall in response to increased blood volume and acts to:

Answer: Dilate blood vessels and promote sodium/water loss, thereby lowering blood pressure.

  • A Increase renin secretion from the juxtaglomerular apparatus
  • B Dilate blood vessels and promote sodium/water loss, thereby lowering blood pressure
  • C Stimulate the adrenal medulla to release more adrenaline
  • D Constrict blood vessels and promote sodium/water retention, raising blood pressure further

Correct answer: B. Dilate blood vessels and promote sodium/water loss, thereby lowering blood pressure

Explanation: ANF is released when the atrial wall is stretched by increased blood volume; it causes vasodilation and increased renal sodium/water excretion, lowering blood pressure.

Hypothalamus-Pituitary Axis (Negative Feedback)Hypothalamusreleasing hormonePituitary("relay", not the boss)trophic hormoneTarget gland (e.g. thyroid, adrenal)hormone outputnegative feedback

The hypothalamus releases hormones that direct the pituitary, which releases its own trophic hormone to a target gland; that gland's hormone output then feeds back (dashed lines) to suppress both the pituitary and hypothalamus once levels are sufficient - a self-correcting loop running the entire endocrine system.

Concept context

The endocrine glands, hormone classification and mechanism of action, and negative feedback regulation.

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