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🔬 Biology  ·  Chemical Coordination and Integration  ·  NEET

An overactive thyroid secreting excess thyroxine causes the condition:

Answer: Hyperthyroidism.

  • A Hyperthyroidism
  • B Hypothyroidism
  • C Infant cretinism
  • D Simple goitre

Correct answer: A. Hyperthyroidism

Explanation: Excess thyroxine (hyperthyroidism) speeds up metabolism, causing weight loss, rapid heartbeat and nervousness.

Hypothalamus-Pituitary Axis (Negative Feedback)Hypothalamusreleasing hormonePituitary("relay", not the boss)trophic hormoneTarget gland (e.g. thyroid, adrenal)hormone outputnegative feedback

The hypothalamus releases hormones that direct the pituitary, which releases its own trophic hormone to a target gland; that gland's hormone output then feeds back (dashed lines) to suppress both the pituitary and hypothalamus once levels are sufficient - a self-correcting loop running the entire endocrine system.

Concept context

The endocrine glands, hormone classification and mechanism of action, and negative feedback regulation.

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