Answer: Pre-replication complex (pre-RC) assembly licensing new DNA replication in G 1.
- A Further condensation of chromosomes ahead of the next cell division in the majority of cases studied
- B Pre-replication complex (pre-RC) assembly licensing new DNA replication in G<sub>1</sub>
- C Disassembly of the spindle apparatus shortly following anaphase onset as widely reported
- D Formation of the cleavage furrow during the cytokinesis process in standard practice
Correct answer: B. Pre-replication complex (pre-RC) assembly licensing new DNA replication in G<sub>1</sub>
Explanation: Geminin inhibits Cdt1, blocking pre-RC assembly. APC/C degrades geminin in late mitosis, allowing Cdt1 to re-license origins for the next S phase.
The cell cycle: G1 (growth and preparation), S (DNA replication, chromosome number stays 2n but DNA content doubles), G2 (final checks before division), and M (mitosis itself) - together, G1+S+G2 make up interphase.
Concept context
Mitosis and meiosis: how cells divide for growth, repair, and reproduction.