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🔬 Biology  ·  Breathing and Exchange of Gases  ·  NEET

Carbon monoxide is poisonous because it binds to haemoglobin far more strongly than:

Answer: oxygen.

  • A oxygen
  • B nitrogen
  • C water
  • D glucose

Correct answer: A. oxygen

Explanation: CO binds haemoglobin about 200 times more tightly than oxygen, blocking oxygen transport.

O₂-Haemoglobin Dissociation CurvepO₂% Hb saturatedresting curveshifted RIGHT (Bohr effect:↑CO₂, ↑H⁺, ↑temperature)Sigmoid shape = cooperative binding; right-shift means O₂ is released more easily in active tissue

The S-shaped (sigmoid) curve reflects cooperative binding between Hb's four O₂ sites; the Bohr effect shifts the whole curve to the right under conditions found in actively respiring tissue (more CO₂, more acid, more heat), making haemoglobin release oxygen more readily exactly where it's needed.

Concept context

The mechanics of breathing, lung volumes, gas transport in blood, the Bohr effect, and respiratory regulation.

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