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🔬 Biology  ·  Biomolecules  ·  NEET

What makes telomerase important for cell immortality?

Answer: It adds telomeric repeats to chromosome ends, preventing shortening.

  • A It repairs double-strand breaks scattered throughout the chromosome arms
  • B It adds telomeric repeats to chromosome ends, preventing shortening
  • C It deposits methyl marks onto histone tails to silence chromosomal regions
  • D It excises the RNA primers left behind after lagging-strand synthesis

Correct answer: B. It adds telomeric repeats to chromosome ends, preventing shortening

Explanation: Telomerase is a reverse transcriptase that extends telomeres. Normal somatic cells lack telomerase, so chromosomes shorten with each division (Hayflick limit). Cancer cells and stem cells reactivate telomerase.

Enzyme Kinetics: Rate vs Substrate Concentration[Substrate]Reaction rateVmaxKm½VmaxCurve flattens at high [S]: ALL enzyme active sites are occupied (saturation)

As substrate concentration rises, reaction rate increases steeply at first, then plateaus at Vmax once every enzyme molecule is working at full capacity; Km is the substrate concentration giving half-maximal rate, and a LOWER Km means the enzyme reaches that rate with less substrate (higher affinity).

Concept context

Carbohydrates, proteins, lipids, nucleic acids, and enzyme kinetics. Essential foundation for understanding metabolism.

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