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🔬 Biology  ·  Neural Control and Coordination  ·  NEET

The Hodgkin-Huxley model of the action potential uses which equation?

Answer: Differential equations with m, h (Na+ channel gating) and n (K+ channel gating) variables derived from voltage-clamp experiments.

  • A Mainly a simple, fixed-threshold equation that includes few voltage-dependent gating variables present in general practice
  • B Differential equations with m, h (Na+ channel gating) and n (K+ channel gating) variables derived from voltage-clamp experiments
  • C Ohm's law alone, relating membrane current directly to voltage and a fixed resistance term value as frequently described in most textbook accounts
  • D The Nernst equation alone, describing mainly the equilibrium potential of a single permeant ion species during normal conditions

Correct answer: B. Differential equations with m, h (Na+ channel gating) and n (K+ channel gating) variables derived from voltage-clamp experiments

Explanation: Hodgkin-Huxley model (1952 Nobel Prize): conductance-based equations using m<sup>3h</sup> (Na+ activation/inactivation) and n<sup>4</sup> (K+ activation) variables, accurately reproducing action potential shape and propagation.

Labeled diagram of a neuron showing dendrites, cell body (soma) with nucleus, axon, myelin sheath, Nodes of Ranvier, and axon terminals

Structure of a neuron. Image: LadyofHats (Mariana Ruiz), Public Domain, via Wikimedia Commons.

Concept context

Brain, spinal cord, neurons, reflex arcs, and sense organs.

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