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🔬 Biology  ·  Molecular Basis of Inheritance  ·  NEET

Which observation provided evidence that RNA can serve as genetic material?

Answer: reconstituted TMV infectivity.

  • A Griffith's mouse transformation
  • B the Meselson-Stahl experiment
  • C the Hershey-Chase blender study
  • D reconstituted TMV infectivity

Correct answer: D. reconstituted TMV infectivity

Explanation: Reconstitution experiments with tobacco mosaic virus showed that its RNA, not its protein coat, carried the infective genetic information.

The Replication Forkhelicase (unwinds fork)leading strand (continuous, 5'→3')lagging strand: Okazaki fragments (discontinuous)

Helicase unwinds the double helix at the replication fork; one new strand (leading) is synthesised continuously toward the fork, while the other (lagging) must be made in short, separate Okazaki fragments because DNA polymerase only adds nucleotides 5'→3'.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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