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🔬 Biology  ·  Molecular Basis of Inheritance  ·  NEET

The wobble hypothesis explains how:

Answer: A single tRNA can recognise more than one codon for the same amino acid.

  • A How ribosomes physically move stepwise along the mRNA strand
  • B A single tRNA can recognise more than one codon for the same amino acid
  • C How RNA polymerase correctly selects the appropriate gene promoter
  • D How spliceosomes remove introns from precursor hnRNA transcripts

Correct answer: B. A single tRNA can recognise more than one codon for the same amino acid

Explanation: The wobble hypothesis states that the pairing at the third codon position can be flexible, letting one tRNA recognise multiple synonymous codons.

The Replication Forkhelicase (unwinds fork)leading strand (continuous, 5'→3')lagging strand: Okazaki fragments (discontinuous)

Helicase unwinds the double helix at the replication fork; one new strand (leading) is synthesised continuously toward the fork, while the other (lagging) must be made in short, separate Okazaki fragments because DNA polymerase only adds nucleotides 5'→3'.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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