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🔬 Biology  ·  Molecular Basis of Inheritance  ·  NEET

In the poly-U experiment, Nirenberg and Matthaei found that UUU codes for:

Answer: the amino acid phenylalanine.

  • A the amino acid proline
  • B the amino acid phenylalanine
  • C a chain-terminating signal
  • D the amino acid methionine

Correct answer: B. the amino acid phenylalanine

Explanation: Using a synthetic poly-U mRNA, Nirenberg and Matthaei obtained a polyphenylalanine chain, establishing that UUU codes for phenylalanine.

The Replication Forkhelicase (unwinds fork)leading strand (continuous, 5'→3')lagging strand: Okazaki fragments (discontinuous)

Helicase unwinds the double helix at the replication fork; one new strand (leading) is synthesised continuously toward the fork, while the other (lagging) must be made in short, separate Okazaki fragments because DNA polymerase only adds nucleotides 5'→3'.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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