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🔬 Biology  ·  Molecular Basis of Inheritance  ·  NEET

Griffith's transforming principle was later shown to be DNA by:

Answer: Avery, MacLeod and McCarty.

  • A Hershey and Martha Chase
  • B Avery, MacLeod and McCarty
  • C Watson, Crick and Wilkins
  • D Meselson and F. Stahl

Correct answer: B. Avery, MacLeod and McCarty

Explanation: Avery, MacLeod and McCarty showed that DNA, not protein or RNA, was the transforming material responsible for Griffith's results.

The Replication Forkhelicase (unwinds fork)leading strand (continuous, 5'→3')lagging strand: Okazaki fragments (discontinuous)

Helicase unwinds the double helix at the replication fork; one new strand (leading) is synthesised continuously toward the fork, while the other (lagging) must be made in short, separate Okazaki fragments because DNA polymerase only adds nucleotides 5'→3'.

Concept context

DNA structure, replication, transcription, translation, the genetic code, and gene regulation (lac operon). The single most important chapter for NEET molecular biology.

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