Zaymiey

🔬 Biology  ·  Cell: The Unit of Life  ·  NEET

The signal hypothesis (Blobel) explains how:

Answer: Secretory proteins are directed to the rough ER.

  • A Nuclear proteins enter the nucleus through pores
  • B Secretory proteins are directed to the rough ER
  • C Mitochondrial proteins are imported through TOM complexes
  • D All organelle proteins are targeted using one universal signal

Correct answer: B. Secretory proteins are directed to the rough ER

Explanation: Blobel's signal hypothesis: N-terminal signal sequence on secretory proteins directs ribosomes to rough ER; protein enters the ER lumen.

Labeled diagram of an animal cell showing nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, and other organelles

Animal cell structure with major organelles labeled. Image: LadyofHats (Mariana Ruiz), Public Domain, via Wikimedia Commons.

Concept context

Cell theory, prokaryotic vs eukaryotic cells, organelles and their functions. Foundation of all biology.

Read the full Cell: The Unit of Life notes →