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🔬 Biology  ·  Cell: The Unit of Life  ·  NEET

KDEL sequence on a protein indicates it should be:

Answer: Retained in the ER lumen.

  • A Secreted out of cell
  • B Targeted to lysosomes
  • C Retained in the ER lumen
  • D Sent to mitochondria

Correct answer: C. Retained in the ER lumen

Explanation: KDEL (Lys-Asp-Glu-Leu) is the ER retention signal. Proteins with KDEL are retrieved from the Golgi and retained in the ER.

Labeled diagram of an animal cell showing nucleus, mitochondria, endoplasmic reticulum, Golgi apparatus, and other organelles

Animal cell structure with major organelles labeled. Image: LadyofHats (Mariana Ruiz), Public Domain, via Wikimedia Commons.

Concept context

Cell theory, prokaryotic vs eukaryotic cells, organelles and their functions. Foundation of all biology.

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