Zaymiey

🔬 Biology  ·  Biotechnology and its Applications  ·  NEET

In producing recombinant insulin by Eli Lilly, the two chains A and B were produced separately and then:

Answer: Joined by disulphide bonds to form human insulin.

  • A Injected separately into patients as two unlinked chains
  • B Left as inactive proinsulin
  • C Joined by disulphide bonds to form human insulin
  • D Converted into the C peptide

Correct answer: C. Joined by disulphide bonds to form human insulin

Explanation: The A and B chains were produced in E. coli and then combined by creating disulphide bonds to form the functional human insulin.

Concept context

GM crops, transgenic animals, gene therapy, molecular diagnostics, and bioethics. Frequent 2–3 mark questions in NEET.

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